ADCs : antibodies and cytotoxic molecules united against tumours

ADC, antibody-drug conjugates, conjugués anticorps médicaments

From Paul Ehrlich’s early “magic bullet” concept to today’s approved therapeutics, Antibody-Drug Conjugates (ADCs) represent a major breakthrough in targeted cancer therapy. By combining the selectivity of monoclonal antibodies with the potency of cytotoxic agents, ADCs aim to eliminate tumor cells while sparing healthy tissues. This article dives into the evolution, design strategies, and key challenges of these complex biologics. 

antibody-drug conjugates

ADCs, market analysis, analyse marché, anticorps conjugués, anticorps armés, monoclonal antibody conjugated, immunoconjugués

This month’s MabDesign market analysis gives you an overview of the antibody-drug conjugates market and projects in development.

Monoclonal antibodies: the stars of therapeutic proteins

mAbs, anticorps monoclonal monoclonaux

Hybridoma technology for the production of monoclonal antibodies (mAbs), awarded the Nobel Prize for Medicine in 1984, revolutionized serotherapy, which previously used patient serum containing mixtures of antibodies. More targeted and therefore more effective, mAbs offer innovative perspectives in the treatment of various diseases, and have become an essential therapeutic strategy in our pharmaceutical arsenal.