Each month, MabDesign’s market analyses provide an overview of the market dynamics and ongoing development projects for a given indication or technology, helping you better understand the constantly evolving field of biopharmaceuticals and bioproduction. This month, we highlight bacteriophage therapies currently under development
Market & pipeline analysis
Antimicrobial resistance (AMR) has become a major global public health threat, with 1.27 million deaths directly attributable each year and nearly 5 million associated deaths in 2019. Without alternative solutions, projections estimate up to 10 million annual deaths by 2050.
In this context, phage therapy, based on the use of bacteriophages to selectively target and destroy pathogenic bacteria, is emerging as a promising therapeutic approach. Unlike antibiotics, phages can be adapted or combined into cocktails to counter the rapid emergence of resistant strains.
Epidemiological data
1,27
million direct deaths in 2019
5
millions associated deaths in 2019
10
millions estimated annual deaths by 2050
Pipeline
The global pipeline shows increasing momentum:
- Clinical-stage projects in multiple indications, including urinary tract infections, chronic inflammatory diseases, and Pseudomonas aeruginosa infections.
Developement stages
Indications
- An ecosystem of innovative actors, from specialized biotechs (Pherecydes Pharma, BiomX, Adaptive Phage Therapeutics, Armata Pharmaceuticals…) to collaborations with major pharmaceutical groups.
Bacteriophage therapies are therefore positioning themselves as a strategic lever against the global antimicrobial resistance crisis, at the crossroads of therapeutic innovation and major public health challenges.
Download our infographic
projets de thérapies basées sur l’édition du génome (gene-editing therapies) actuellement en développement. (2025)
Want to know more?
MabDesign has acquired and cultivated expertise in all market segments associated with biopharmaceuticals and biomanufacturing. Our team of consultants is available to assist you with all your biotherapy-related projects. Feel free to explore our range of services, including our marketing and strategic analyses, if you would like to learn more!
Sources : MabDesign & GlobalData
Date – Août 2025
