{"id":35878,"date":"2025-10-09T10:00:00","date_gmt":"2025-10-09T08:00:00","guid":{"rendered":"https:\/\/mabdesign.fr\/?p=35878"},"modified":"2025-10-03T10:13:57","modified_gmt":"2025-10-03T08:13:57","slug":"zoom-on-mcsaf","status":"publish","type":"post","link":"https:\/\/mabdesign.fr\/en\/zoom-on-mcsaf\/","title":{"rendered":"ZOOM ON &#8211; McSAF"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"35878\" class=\"elementor elementor-35878\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5e41cebf e-flex e-con-boxed e-con e-parent\" data-id=\"5e41cebf\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3316e936 e-con-full e-flex e-con e-child\" data-id=\"3316e936\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6777355b elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"6777355b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"285\" height=\"100\" src=\"https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/McSAF-Logo-01_IV_sign_CMJN-ls.jpg\" class=\"attachment-large size-large wp-image-35889\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1a026219 e-con-full e-flex e-con e-child\" data-id=\"1a026219\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4bba56eb elementor-widget elementor-widget-heading\" data-id=\"4bba56eb\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Who are you?<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f9866e2 elementor-widget elementor-widget-text-editor\" data-id=\"f9866e2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>McSAF is a French biotech which develops technologies for <b>stable and homogeneous<\/b> <b>Antibody-Drug Conjugates<\/b> (5 proprietary technology patents).<\/p>\n<p>\u00a0<\/p>\n<p>ADC revolutionized the oncological environment and are part of the boiling modalities in targeted therapy.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4964771e e-flex e-con-boxed e-con e-parent\" data-id=\"4964771e\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-31372dd6 e-flex e-con-boxed e-con e-parent\" data-id=\"31372dd6\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2db44102 elementor-widget elementor-widget-heading\" data-id=\"2db44102\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">What is your expertise?<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a624962 elementor-widget elementor-widget-text-editor\" data-id=\"2a624962\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Our innovation focuses on the bioconjugation head, which is compatible with various types of proteins (including native antibodies and fragments), as well as a range of linkers and payloads.<\/p>\n<p>\u00a0<\/p>\n<p>Our approach involves site-specific bioconjugation on cysteine bridges, enabling precise control over the position of the linker and payload in the upper region of the antibody. This method avoids interference with both the Fc and CDR regions.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1d4df5bb e-flex e-con-boxed e-con e-parent\" data-id=\"1d4df5bb\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-24a94e5c elementor-widget elementor-widget-heading\" data-id=\"24a94e5c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">What are your key products or services?<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-568f5cc9 elementor-widget elementor-widget-text-editor\" data-id=\"568f5cc9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>ADCs cover a wide range of applications and are no longer limited to chemo-type molecules. Our tools are compatible with classic payloads (auristatin, topoisomerase inhibitors, DNA alkylating agents\u2026) and are also compatible with oligonucleotides and radionuclides.<\/p>\n<p>\u00a0<\/p>\n<p><b>We offer design and production at lab scale of<\/b><b>:<\/b><\/p>\n<p>\u00a0<\/p>\n<ul>\n<li><b>DAR 1, 2, and 4 ADCs <\/b><\/li>\n<li><b>and DUAL products, carrying two different payloads for complementary mechanism of action<\/b><\/li>\n<li><b>always with controlled DAR, homogeneity and stability. <\/b><\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3297c97 elementor-widget elementor-widget-image\" data-id=\"3297c97\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"455\" src=\"https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Capture-decran-2025-10-03-095358.png\" class=\"attachment-large size-large wp-image-35893\" alt=\"\" srcset=\"https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Capture-decran-2025-10-03-095358.png 847w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Capture-decran-2025-10-03-095358-300x171.png 300w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Capture-decran-2025-10-03-095358-768x437.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-75824302 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"75824302\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"http:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/ZOOM-ON-LinkedIn-McSAF.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Download the ZOOM ON<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7a011ada e-flex e-con-boxed e-con e-parent\" data-id=\"7a011ada\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;,&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-752c34fa e-con-full e-flex e-con e-child\" data-id=\"752c34fa\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3ee65373 elementor-widget elementor-widget-heading\" data-id=\"3ee65373\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Vous souhaitez en savoir plus? <\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-726094ce e-con-full e-flex e-con e-child\" data-id=\"726094ce\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t<div class=\"elementor-element elementor-element-600f42c7 e-con-full e-flex e-con e-child\" data-id=\"600f42c7\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7a8b07dd elementor-widget elementor-widget-text-editor\" data-id=\"7a8b07dd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Audrey Desgranges<\/strong><\/p>\n<p>Director of Operations<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f5d007e e-con-full e-flex e-con e-child\" data-id=\"f5d007e\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-35ac7905 elementor-widget__width-initial elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"35ac7905\" data-element_type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 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elementor-element-5b8e54cc elementor-widget elementor-widget-text-editor\" data-id=\"5b8e54cc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>(+33) 6 34 63 69 77<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2e33c9cc elementor-widget elementor-widget-text-editor\" data-id=\"2e33c9cc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"CCgQ5 vCa9Yd QfkTvb N8QANc Va3FIb EE3Upf\" role=\"heading\" aria-level=\"3\"><a href=\"http:\/\/mcsaf.fr\/\"><span class=\"yIn8Od DPAWn\"><span class=\"wbJOMb\"><span class=\"OSrXXb VN4UC chcHdb\"><span class=\"x2VHCd OSrXXb ob9lvb\" role=\"text\" data-dtld=\"revvity.com\">https:\/\/www.mcsaf.fr<\/span><\/span><\/span><\/span><\/a><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-20aebc27 e-con-full e-flex e-con e-child\" data-id=\"20aebc27\" data-element_type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4094e908 elementor-widget elementor-widget-image\" data-id=\"4094e908\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"452\" src=\"https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Plan-de-travail-1@4x-1024x578.png\" class=\"attachment-large size-large wp-image-35895\" alt=\"\" srcset=\"https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Plan-de-travail-1@4x-1024x578.png 1024w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Plan-de-travail-1@4x-300x169.png 300w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Plan-de-travail-1@4x-768x433.png 768w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Plan-de-travail-1@4x-1536x867.png 1536w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2025\/10\/Plan-de-travail-1@4x.png 2001w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-62369caf elementor-widget elementor-widget-text-editor\" data-id=\"62369caf\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Member of<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c61307a elementor-widget elementor-widget-image\" data-id=\"c61307a\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"236\" src=\"https:\/\/mabdesign.fr\/wp-content\/uploads\/2024\/12\/22-05-17_LOGO-MABDESIGN-22-BLANC.png\" class=\"attachment-large size-large wp-image-26615\" alt=\"MabDesign\" srcset=\"https:\/\/mabdesign.fr\/wp-content\/uploads\/2024\/12\/22-05-17_LOGO-MABDESIGN-22-BLANC.png 819w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2024\/12\/22-05-17_LOGO-MABDESIGN-22-BLANC-300x89.png 300w, https:\/\/mabdesign.fr\/wp-content\/uploads\/2024\/12\/22-05-17_LOGO-MABDESIGN-22-BLANC-768x227.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>McSAF is a French biotech which develops technologies for stable and homogeneous Antibody-Drug Conjugates (5 proprietary technology patents).<br \/>\n\u00a0<br \/>\nADC revolutionized the oncological environment and are part of the boiling modalities in targeted therapy.<\/p>\n","protected":false},"author":6,"featured_media":35874,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9,11],"tags":[],"class_list":["post-35878","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites","category-zoom-on"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ZOOM ON - McSAF - MabDesign<\/title>\n<meta name=\"description\" content=\"McSAF is a French biotech which develops technologies for stable and homogeneous Antibody-Drug Conjugates (5 proprietary technology patents). \u00a0 ADC revolutionized the oncological environment and are part of the boiling modalities 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