{"id":17458,"date":"2023-04-28T07:45:54","date_gmt":"2023-04-28T05:45:54","guid":{"rendered":"http:\/\/mabdesign.fr\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/"},"modified":"2023-04-28T07:45:54","modified_gmt":"2023-04-28T05:45:54","slug":"cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine","status":"publish","type":"post","link":"https:\/\/mabdesign.fr\/en\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/","title":{"rendered":"Cynbiose and VIRNEXT have contributed to the preclinical assessment and accelerated transfer to clinical trial of HIPRA Covid-19 vaccine"},"content":{"rendered":"<p><strong>CYNBIOSE AND VIRNEXT CONGRATULATE THE PHARMACEUTICAL COMPANY HIPRA UPON COVID-19 VACCINE\u2019S, BIMERVAX\u00ae, APPROVAL BY THE EUROPEAN MEDICINES AGENCY (EMA)<\/strong><\/p>\n<p>Lyon, France, April 25th, 2023 &#8211; <strong>CYNBIOSE<\/strong>, a service company specializing in the development of innovative preclinical models, in partnership with VIRNEXT, a technological platform specializing in respiratory infectious diseases and evaluation of prophylactic and therapeutic treatments, have contributed actively to the preclinical assessment and accelerated transfer to clinical trial of HIPRA\u2019s Covid-19 vaccine. At the time the SARS-CoV-2 pandemic was at its peak, HIPRA, a biotechnological pharmaceutical company, initiated a preclinical evaluation of its vaccine candidate to confirm its safety and efficacy in a translational model.<br \/>\nThe active component of the HIPRA Covid-19 vaccine is an heterologous recombinant heterodimer protein that emulates the receptor binding domain (RBD) of the Spike (S) protein of the Alpha and Beta variants of the SARS-Cov-2 virus. The antigen, which is the active component of the vaccine, requires an adjuvant to amplify and enhance the immune response.<br \/>\nThe preclinical trials were completed in 2021. The European Commission announced in August 2022 it had signed a pre-purchase agreement with HIPRA to supply its Covid-19 vaccine, subject to approval by the European Medicines Agency (EMA). The agreement involves 13 countries and should allow the purchase of up to 250 million doses, said the European executive in a statement1.<br \/>\nCYNBIOSE and VIRNEXT were selected to perform the preclinical studies in a SARS-CoV-2 large animal efficacy model. <a href=\"http:\/\/mabdesign.fr\/wp-content\/uploads\/2023\/04\/HIPRA-Covid-vaccine-Cynbiose-VirNext-VF-25042023.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">To know more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CYNBIOSE in partnership with VIRNEXT, a technological platform specializing in respiratory infectious diseases and evaluation of prophylactic and therapeutic treatments, have contributed actively to the preclinical assessment and accelerated transfer to clinical trial of HIPRA\u2019s Covid-19 vaccine.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36,32],"tags":[],"class_list":["post-17458","post","type-post","status-publish","format-standard","hentry","category-news","category-our-members"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - 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MabDesign\" \/>\n<meta property=\"og:description\" content=\"CYNBIOSE in partnership with VIRNEXT, a technological platform specializing in respiratory infectious diseases and evaluation of prophylactic and therapeutic treatments, have contributed actively to the preclinical assessment and accelerated transfer to clinical trial of HIPRA\u2019s Covid-19 vaccine.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mabdesign.fr\/en\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/\" \/>\n<meta property=\"og:site_name\" content=\"MabDesign\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-28T05:45:54+00:00\" \/>\n<meta name=\"author\" content=\"alexis.mathias@kairios.fr\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@MabDesign_fr\" \/>\n<meta name=\"twitter:site\" content=\"@MabDesign_fr\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"alexis.mathias@kairios.fr\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/mabdesign.fr\/en\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/mabdesign.fr\/en\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/\"},\"author\":{\"name\":\"alexis.mathias@kairios.fr\",\"@id\":\"https:\/\/mabdesign.fr\/en\/#\/schema\/person\/0a9d0510f7433c83f9e6974b2a9c0135\"},\"headline\":\"Cynbiose and VIRNEXT have contributed to the preclinical assessment and accelerated transfer to clinical trial of HIPRA Covid-19 vaccine\",\"datePublished\":\"2023-04-28T05:45:54+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/mabdesign.fr\/en\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/\"},\"wordCount\":257,\"publisher\":{\"@id\":\"https:\/\/mabdesign.fr\/en\/#organization\"},\"articleSection\":[\"News\",\"Our members\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/mabdesign.fr\/en\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/\",\"url\":\"https:\/\/mabdesign.fr\/en\/cynbiose-and-virnext-have-contributed-to-the-preclinical-assessment-and-accelerated-transfer-to-clinical-trial-of-hipra-covid-19-vaccine\/\",\"name\":\"Cynbiose and VIRNEXT have contributed to the preclinical assessment and accelerated transfer to clinical trial of HIPRA Covid-19 vaccine - 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